gneet's Digestion and Absorption notes

Biology Index


Nutrition is a process by which animals obtain essential and nonessential substances called nutrients and utilize these produce to energy required for various life process such as growth, repair, development, reproduction and other activities from the surrounding as food.
Modes of nutrition

  1. Autotrophic nutrition
    Preparation of organic food from the inorganic materials is called autotrophic nutrition It is of two types : Photoautotrophic and chemoautotrophic
  1. Photoautotrophic nutrition
    All green plants, certain protists ( Euglena viridis) and some bacterial ( green sulphur bacterium, chlorobium) take carbon dioxide and water from the environment and transform these into glucose and oxygen with the help of Sun’s energy trapped by chlorophyll.
  2. Chemoautotrophic nutrition
    Some bacteria utilize light as source of energy during the synthesis of food, utilize the energy obtained in the form of A.T.P
Examples of chemoautotrophic bacteria
  1. Sulphur bacteria – Beggiatoa, thiothrix and Thiobacillus thiooxidans
  2. Iron bacteria
  3. Nitrifying bacteria – Nitrosomonas, Nitrosococcus, Nitrobacter and Nitrocystis

Hetrotrophic nutrition

Animals, fungi etc cannot manufacture their food. They depends upon autotrophs directly or indirectly.
  1. Holotrophic ( Holozoic) nutrition
    Most vertebrates and invertebrates take solid or liquid food through their mouth is called holozoic nutrition
  2. Saprozoic nutrition
    It consists of obtaining food from dead and decaying organic food by first pouring digestive juices over the same and then sucking the digested food. Example – Spider, housefly
  3. Parasitic nutrition
    In this type of nutrition, food is obtained in liquid form from the body of another killing him Example – Plasmodium, Trypanosoma, Taenia, ascaris

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Mouth and teeth

It is a system of alimentary canal and digestive glands that takes part in ingestion of food, its crushing, digestion, absorption of digested nutrients and egestion of undigested materials.



It is a narrow space enclosed between the lips and checks externally and the gums and teeth internally.

Oral ( Buccal) cavity

It is a space bounded above by the palate, below by the throat and on the sides by the jaws.
The buccal cavity is lined by stratified squamous epithelium.


The anterior part of palate is arched and strong. It is called hard palate. This part is well supported by maxilla bone.


  1. Vallate ( surrounded by wall)
  2. Fungiform ( mushroom shaped)
  3. Foliate ( leaf –shaped)
  4. Filiform ( filament-shaped)

Function of the tongue

  1. It helps in chewing the food.
  2. It plays a role in speech.
  3. It aids in swallowing the food and mixing the food and saliva.
  4. It acts as brush to clear the teeth by cleaning small food particles.
  5. It is an organ of taste and can recognize four tastes, i.e. salty, sweet, bitter and sour.


Types of teeth

Structure of teeth

  1. Crown: It is the exposed portion of tooth above the gums ( gingiva)
    • The gingiva is a specialized region of the oral mucosa surrounding the neck of the teeth
    • Crown is covered with the hardest substances called enamel that protects the crown
    • Beneath the enamel is dentine which is made up of hard substances but are not tough as enamel and they can decay
    • Dentine forms the bulk of the tooth. There is a pulp cavity inside the dentine. It is jelly like substance and carries the nerves fibres, blood vessels and sensory cells.
    • The nerves supply to the upper teeth is by the branches of maxillary nerves and to the lower teeth by the branches of mandibular nerves. These both are branches of 5th cranial nerve called trigeminal nerve.
  2. Neck: It is a narrow portion at the gumline.
  3. Root: It is embedded in the jaw bone and holds the tooth securely in place.
    The root is fixed in alveolus of the jaw bone by periodontal membrane and cementum. Cement holds a tooth in its socket and periodontal membrane covers the cement.

Number of teeth

Dental formulae

The number and kinds of teeth in mammals are represented by an equation called dental formula. This equation looks like
I = Incisors, C = Canines Pm = Premolars
Total number of teeth = Number of teeth in dental formula × 2
Dental formula of some animals

Dentition of animals

1. Aerodont
Part of bone, not embedded in sockets eg. Reptiles, except crocodiles
2. Theocodont
Embedded in deep socket of some jaw bones e.g. mammals, crocodiles
3. Monophycodont
Teeth grow only once in life e.g. platypus, toothed whale.
4. Diphyodont
All teeth, except molar, grow twice in life. Eg. Mammals
5. Polyphyodont
Fallen or wornout teeth can be replaced many times throughout life. Eg. Frog
6. Isodont
All teeth are similar Eg. Tooth whale
7. Heterodont
More than one type of teeth E.g mammals, crocodiles

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Parts of digestive systems


The mouth leads to funnel shaped pharynx. The pharynx is about 12cm long vertical canal beyond the soft palate. The food and air passages cross here. The pharynx may be divided into three parts

  1. Nasopharynx: Upper part of PharynxHave internal nares in the root, oval opening of Eustachion tubes
  2. OropharynxMiddle part of pharynxHas palatine tonsils
  3. Laryngopharynx

Waldeyer’s ring

All lymphoid tissues are active in production of immunoglobulin
  1. Nasopharyngeal tonsils
    • In children nasopharyngeal tonsil become enlarged and is then referred to as adenoids
    • The resulting swelling causes obstruction to normal breathing
  2. Tubal tonsils
    Lymphoid tissue found around the opening of each Eustachian tube
  3. Palatine tonsils
    • Located in the lateral wall of oropharynx
    • The palatine tonsils is often infected leading to sore throat and surgical removal of such enlarged tonsils become necessary
  4. Lingual tonsils
    Lymphoid tissue present at the base of tongue


  1. Cardiac part: It is so called because it is present near the heart. The cardic sphincter lies in the opening between oesophagus and stomach. It is a functional valve. Cardiac gland secrete mucus
  2. Fundus: It extends superiorly from the cardiac part. The fundus is commonly filled with gas or air. Fundic glands secretes HCl and intrinsic factor
  3. Body :It is main part stomach
  4. Pyloric part : It is the distal part of stomach. The pyloric region is divided into the pyloric antrum and pyloric canal. The pyloric sphincter guards the opening between the stomach and duodenum and periodically permits partially digested food to leave the stomach and ether duodenum. Pyloric glands secrete gastrin produced by their G-cells

stomach anatomy


  1. Storage: the stomach allows a meal to be consumed and the material to be consumed and the materials released incrementally into the duodenum from digestion
  2. Chemical digestion: Pepsin begins the process of protein digestion cleaving large polypeptides into shorter chains
  3. Mechanical digestion: The churning action of muscularis causes liquifaction and mixing of the contents to produce acid chyme
  4. Some absorption: Water, electrolyte monosaccharides and fat soluble molecules including alcohol are all absorbed in stomach to some degrees.

Ruminant Stomach

In ruminants, the stomach is differentiated into chambers
  1. Large rumen for churning, breaking of food by cornified surface of villi, fermentation of cellulose by symbiotic microorganism
  2. Recticulum
  3. Omasum for mechanical churning and breaking of food, absorption of fluid
  4. Abomasum for mixing gastric juice, ruminates the chew cud. This is done by breaking small part of food present in rumen and sending it to buccal cavity for chewing. Omasumis absent in camel. Here rumen and reticulum have water pockets for temporary storage of food. Abomasum functions as true stomach.

Small intestine

The small intestine is a narrow tube , about 6 metres long in a living adult. It is longest part of alimentary canal. It comprises of alimentary canal.
It comprises of three parts: duodenum, jejunum and ileum

  1. Duodenum: It is a C-shaped structure and about 25 cm long. It receives the hepatopancreatic duct formed by union of bile duct (from liver) and pancreatic duct ( from pancreas) and whose opening is guarded by sphincter of oddi. Small nodules of lymphoid tissue are seen along the entire length of small intestine. These nodules are call Payer’s patches
  2. Jejunum: It is slightly coiled moderately wide ( 3.5 – 4 cm) middle part of small intestine. Its wall is thicker and more vascular than that of illum. Jejunum is rich in digestive glands villi are rounded. Its length is about 0.8 – 1.5m
  3. Ileum: the ileum forms the lower part of small intestine. It is about 3.5 m long, and opens into large intestine. It is characterized by club-shaped villi and Peyer’s patches. Villi increases internal surface of ileum by about 10 times. Peye’s patches contain higher concentration of white blood cells that helps protect the body from infection and disease


  1. The small intestine completes digestion of proteins, carbohydrate, nucleic acids and fats.
  2. It absorbs nutrient materials into the blood and lymph and also lubrication of food.
  3. It secretes certain hormones such as cholecystokinin, secretin, enterogastrone, duocrinin, enterocrinin and villikinin.
Most nutrient absorption occurs in the small intestine including minerals, vitamins, proteins, and fats. Iron, calcium, magnesium, and zinc are absorbed almost immediately after leaving the stomach – ie, in the 8 feet of the duodenum and the jejunum.
Sugars and vitamin C, as well as thiamin, riboflavin, pyridoxine, and folic acid, are absorbed in the upper third of the small intestine. Protein is absorbed approximately midway through the ileum.
Water and lipids are absorbed by passive diffusion throughout the small intestine.
Sodium bicarbonate is absorbed by active ransport and glucose and amino acid co-transport.Vitamins A, D, E, and K, fats, and cholesterol are absorbed in the lower third of the ileum. Vitamin B12 is absorbed just before the small intestine joins the large intestine. Bile salts are reabsorbed in the distal ileum and the ascending colon.

Large intestine

  1. Caecum and vermiform appendix:
    The caecum is a pouch – like structure which is about 6cm. the caecum is called ileocoecaljunction guarded by ileocaecal valve which prevent back flow. The vermiform appendix is an outgrowth of the caecum. It is a slightly about 8 cm long. Its wall contains prominent lymphoid tissue. Appendix is thought to be vestigial. The inflammation of vermiform appendix due to decay of food or warm infection is called appendicitis and rupture of appendix leads to spilling of faecal matter onto the peritoneum leading to infection and inflammation known as peritonitis.
    The caecum is well developed in herbivorous mammals like, horse, rabbit, etc.
  2. Colon: The caecum leads into the colon, which is divided into four region, the ascending, transverse, descending and sigmoid colon. The sigmoid colon is S-shaped and enters the pelvis and joins the rectum. Ascending colon is shortest part of the colon
    The right colic flexure marks the boundary between the ascending and transverse colon; the left flexure ( splenic flexure) marks the boundary between the transverse and descending colon
  3. Rectum: the sigmoid colon opens into the rectum. The rectum comprises the last 20cm of the digestive tract and terminates 2cm long anal canal. The mucosa of anal canal is folded into several vertical folds, called anal columns, supplied with arteries and veins
  • The opening of anal canal is called anus. The anus has internal anal sphincter composed of smooth muscle fibres and external anal sphincter comprised of striped muscle fibres
  • Structures formed due to enlargement of venis of anal columns in anal canal as well as anus are called haemorrhoids or piles


  1. The large intestine does not secrete enzymes. It plays a minor role in the absorption of nutrients. It stores unabsorbed food remnants temporarily, concentrates the contents by absorbing water to form faeces and the movement of the colon helps to avoid faecus through anus
  2. It also play role in digestion and excretion
  3. The colon bacteria ( E. Coli) produce vitamins B and K which are absorbed

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Histology of human gut

Insert the diagram.
It is a hollow tube having a central cavity or lumen surrounded by a distensible wall, wall of gut is differentiated into four regions which starting from outside to inside are serosa, muscuaris, externa, submucosa and mucosa

  1. Serosa: It is fibrous outer coat or covering layer of gut. Serous consists of two parts, visceral peritoneum and a sheet of loose connective tissue called subserosa
  2. Muscularisexterna( muscular coat): It is quite thick in the region of stomach and proximal part of intestine muscularisexterna has an outer layer of longitudinal smooth fibres followed by a thick layer of circular smooth muscles. Another layer of oblique muscle fibres occurs in stomach inner to circular muscle fibres. On contraction, circular muscular muscle fibres bring about narrowing of gut while longitudinal muscle fibres cause shortening of gut
  3. Submucosa. It is a layer of connective tissues that lies below the muscularisexterna. Submucosa contains nerves, blood vessels and lymph vessels. The tissue has a lot of collagen and elastin fibres for permitting changes in transverse and longitudinal dimensions
  4. Mucosa: It is the innermost which is thrown into circular folds or plical circulars ( valves of kerking or valvulaeconniventes) in the region of intestine. Longitudinal folds or rugal occur in case of empty stomach. Circular folds slow down the movement of food through the intestine. The intestinal wall also bears millions of microscopic figure like projections called villi. Mucosa is differentiated into three layer, namely epithelium, lamina propria and muscularis mucosae
  1. Epithelium
    These are columnar cell and possess upto 3000 microvilli on their free surface.
    Goblet or mucous cells are columnar shaped glandular cells which secrete mucus. Mucus functions as lubricant. It protects the wall of gut from action of proteolytic enzymes. Mucus further provides protection to the epithelium against abrasion or excoriation.
    Epithelium bears a number of pits. The pits bears deep tubular glands in stomach and upper duodenum. They are called crypts of Lieberkuhn in the region of intestine.
  2. Lamina propia
    It is a layer of aerolar reticular connective tissue which contains some scattered smooth muscles cells, blood, capillaries, lymph vessels and non-medullated nerve fibres. It possesPeyer’s patches.
  3. Mucularis mucosae:
    It forms the outer boundary of mucosa that possesses smooth longitudinal muscle fibresexternally and smooth circular muscle fibres internally.

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Digestive glands

Salivary glands:

There are three pairs of salivary glands : parotid, sublingual and submaxillary or submandibular.
  1. Parotid glands: These are the largest salivary glands. They lie on the sides of the face, just below and in front of ears. Viral infection of parotid glands causing swelling and pain, is the disease called mumps.
  2. Sublingual glands: These lie under thefront part of the tongue
  3. Submaxillary glands: These lie at the angles of the lower jaw. The submaxillary ducts, also known as wharton’s ducts open under the tongue
Salivary glands



  1. It moistens and lubricates the buccal cavity, tongue and lips, thus making speech possible.
  2. It also moistens food and changes it to semi-solid mass for easy swallowing
  3. Saliva washes mouth and tongue clear of food debris.
  4. Its enzyme help in digestion.

Gastric glands

gastric gland

Gastric juice

The secretion of the cells of gastric glands from gastric juice with pH 2 – 3.7. About 2,000 to 3,000 ml of gastric juice is secreted per day.


  1. ( Inorganic salts: Bicarbonates, chlorides, carbonates and phosphates of sodium, potassium and calcium
  2. Bile salts: Sodium taurocholate and sodium glycocholate,. They are partly water soluble and partly fat soluble
  3. Fatty substances: Cholesterol, lecithin and other phospholipids
  4. Bile pigments: Bilirubin ( yellowish) and biliverdin (greenish). Other minor bile pigment are bilicyanin, bilipresin, bilifusun, bilihumin and bilifulvin

Functions of liver

  1. Secretion of bile
  2. Deamination – It is a process by which the amino group (-NH2) is removed from amino acids resulting the production of ammonia which is converted into urea
  3. Excretion
    • Liver synthesis urea with the help of ammonia and carbon doxide urea is passed out through excretory system.
    • The bile contains bile pigments ( bilirubin and biliverdin) are excretory products.
    • The liver cells also eliminate certain other waste products like cholesterol, metal ions and waste products of haemoglobin.
  4. Glycogenesis : It is the conversion of the excess of glucose into glycogen by liver cells with the help of insulin secreted by pancreas.
  5. Glycogenolysis: It is the conversion of glycogen into glucose by the liver cells with the help of glucagon secreted by pancreas.
  6. Lipogenesis: It is the conversion of glucose and amino acids into fats which takes place in liver.
  7. Gluconeogenesis: It is the formation of glucose or glycogen from non-carbohydrate sources like amino acids, fatty acids etc.
  8. Detoxification: Liver converts toxic substances into harmless substances
  9. Haemopoiesis: The process of formation of blood corpuscles is called haemopoiesis. The liver produces red blood corpuscles in the embryo.
  10. Synthesis of blood protein: The liver produces blood protein such as prothrombin and fibrinogen that help in the clotting of blood.
  11. Secretion of heparin- Liver secretes heparin ( anticoagulant).
  12. Lymph formation: Liver is important for lymph formation
  13. Synthesis of vitamin-A from B-carotene.
  14. Destruction of R.B.C. : The old worn out red blood corpuscles are broken down in the liver cells. Their haemoglobin is changed into bile pigments.
  15. Phagocytosis: the Kupffer’s cells of the liver engulf the disease causing microorganisms, dead cells and foreign matter
  16. Osmoregulation: Liver produces angiotensinogen which helps kidneys in maintaining body fluid osmoregulation through the action of renin on angiotensin.


The pancreas is soft, lobulated grayish – pink gland which weighs about 60 grams. It is about 2.5cm wide and 12-15 cm long, located posterior to the stomach in the abdominal cavity.

External structure of pancreas

Intestinal glands

The intestinal glands are numerous and microscopic. These are 2 types; crypts of Lieberkuhn and Brunner’s gland.
  1. The crypts of lieberkuhn are simple tubular glands and occur throughout the small intestine between the villi. They have two types of cells.
    1. Paneth cells are found particularly in the duodenum. These cells are rich in zinc and contain acidophilic granules. They secrete lysozyme ( antibacterial substance)
    2. Argentaffin cells is located among epithelial cells and is common in duodenum. It secretes serotonin. Serotonin is a powerful stimulant of smooth muscle, resulting in contraction and play a role in stimulating peristaltic activity of the intestine.
  2. The Brunner’s gland are branched tubular glands and are confined to the duodenum. They secrete alkaline watery fluid, little enzyme and mucus. The mixture of secretions is called intestinal juice or success entericus
  3. About 2 to 3 litres of succusentericus is secreted every day.
    It is alkalin( ph = 8.3) and contains many enzyme amino peptideases, dipeptidases, intestinal amylases, maltase, isomaltase, nucleo-sidases.

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Process of digestion

Digestion is the breakdown of large complex insoluble organic food molecules into small, simpler soluble and diffusible particles by the action of digestive enzymes.

Digestion in mouth

Digestion by Stomach

Digestion by intestine

pH of digestive system

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Neural control of digestion

Digestive hormones in gastrointestinal tract- Summary

Hormone Gastrin

produced by Gastric antrum, duodenum ( Gcells)
it stimulatesecretion of gastricacid and intrinsic factor from parietal cells,
stimulate secretion of pepsinogen from chief cells also promotesgastric and intestinal motility , mucosal growth

Cholecystokinin (CCK)

produced by Duodenum, jejunum ( I cells)
it stimulates gall bladder contraction
stimulates release of pancreatetic enzyme
relaxes sphincter of Oddi for release of bile and enzymes, role is inducing satiety.


produced by Duodenum, jejunum ( S cells)
it stimulates secretion of HCO3 frompancrease
inhibits gastrin and gastric acid secretion

Vasoactive intestinal peptide (VIP)

produced by Enteric nerves
it increases water and electrolyte secretion from pancreas and gut
relaxes smooth muscles ( via nitric oxide)of gut.

Gastric inhibitory polypeptide (GIP)

produced by Duodenum, jejunum ( K cells)
reducesgastric acid secretion and intestinal motility
stimulates insulin release.


Produced by Stomach small intestine and pancreas (D cells)
it inhibits secretion and action of many hormones
including all of the above.

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Absorption of digested food


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Nutritional requirement

Carbohydrates , Proteins and Facts

  1. Carbohydrates
    • The sources of carbohydrates in our diet are cereals ( rice, wheat, maize), potato, grams, fruits ( banana, mango, melon), sugar, honey, sugarcane, beet, jam and milk.
    • An adult man of average weight and doing moderate work needs about 350-500gms of carbohydrates daily.
  2. Proteins
    • The sources of proteins in our diet are cereals, pulses, oil, seeds and nuts, fish, egg, milk, soyabean, cheese, leafy vegetable.
    • About 70 – 100 gms of protein are needed daily.
  3. Fats
    • The sources of fats in our diet are vegetable cooking oil, ghee, butter, chese, eggs.
    • About 50gms of fat is needed daily.

Fat soluble vitamins

  1. Vitamin – A
    • Sources: Milk, butter, maize, carrot, papaya, spinach.
    • Deficiency causes night blindness drying of eyeball etc.
  2. Vitamin – D
    • Sources: Sunlight, cod liver oil, eggs.
    • Deficiency causes rickets.
    • Increases intestinal absorption of calcium and phosphorous.
  3. Vitamin – E
    • Sources : green vegetables, vegetable oil.
    • Deficiency causes reproduction failure, slow growth, anemia.
  4. Vitamin – K
    • Sources: Leafy vegetables.
    • Deficiency causes profuse and prolonged delay in blood clotting,

Water soluble vitamins

  1. Vitamin B1
    • Sources : yeast, sprouted beans, nuts, pulses, cereal.
    • Deficiency causes beriberi, loss of appetite, accumulation of keto acids in blood.
  2. Vitamin B2
    • Sources: yogurt, milk, green vegetables.
    • Deficiency causes skin disorder, headache, cheilosis ( sores at corner of mouth)
  3. VitaminB3
    • sources: pulses, liver, fish.
    • Deficiency causes pellagra, gum diseases, skin problems.
  4. Vitamin B5
    • Sources: eggs, milk, ground nut and tomatoes.
    • Deficiency causes fatigue, muscle cramp, poor motor coordination .
  5. Vitamin B6
    • Sources: All plant and animal tissues.
    • Deficiency cause anemia, diarrhea, nausea and vomiting.
  6. Vitamin B12
    • Sources: Meat, fish, egg, milk.
    • Deficiency causes nervous disorder.
  7. Vitamin C
    • Sources: All citrus fruit.
    • Deficiency causes scurvy, bleeding from small vessels.


  1. Sodium
    • The sources are table salt, beef, spinach.
    • It maintains electric potential across the membrane. It maintains pH balance of our body.
    • Deficiency of sodium causes cramps, diarrhea and dehydration, low blood pressure.
  2. Potassium
    • The sources are banana, orange, milk, spinach.
    • It helps to retain water in cells. Maintains osmotic pressure.
    • Deficiency causes muscle disorder low BP.
  3. Chlorine
    • The sources are table salt, cabbage, cheese.
    • It helps in regulation of osmotic pressure. It helps in formation of HCl in stomach.
    • Deficiency of loss of appetite, causes cramps.
  4. Calcium
    • The sources are milk, green leafy vegetables, cheese, cereals.
    • Helps in clotting of blood. It helps in building of bones and teeth.
    • Deficiency causes rickets, muscle spasms, retarded body growth.
  5. Phosphorous
    • The sources are cereal grains, milk, meat, peas, cheese.
    • It required for tooth and bone formation. It helps regulation of heart beat
    • Deficiency causes metabolic disorders.
  6. Iron
    • Sources: Oatmeal, honey, dates, eggs, spinach, pulses.
    • Importance : Formation of haemoglobin.
    • Deficiency causes: Weakness and weak immunity.

  1. Iodine:
    • Sources: Onion, table salt
    • Causes goiter ( Deficiency)
  2. Sulphur
    • Sources : Meats, daily products
    • Importance: It helps to keep hair skin and nails healthy
    • Deficiency causes unhealthy growth of skin and hair
  3. Magnesium
    • Sources: Dairy products, green leafy vegetable, chocolate.
    • It helps in muscle relaxation
    • Deficiency causes hallucinations, irregularities of metabolism
  4. Copper
    • Sources: Peanuts, beet, barley, soyabean, onion
    • It helps in development of blood vessels and connective tissue
    • Deficiency causes anemia
  5. Chromium
    • Sources : Black gram, soyabean, carrot.
    • It promotes insulin action in the metabolism of sugar
    • Deficiency of nitrogenous waste products
  6. Fluorine
    • Sources: tea, city water supply.
    • It maintains normal enamel and check dental caries.
    • Deficiency causes weak teeth which are prone to decay.
  7. Zinc
    • Sources: Barley, soyabean, groundnut, egg, almond.
    • It hastens healing of wounds. It is needed for healthy skin and hair
    • Deficiency causes retarded growth rough skin and weak immunity.
  8. Cobalt
    • Sources: Milk.
    • Deficiency causes anemia
  9. Manganese
    • Sources: Nuts, legumes.
    • It is important for reproduction and synthesis of haemoglobin.
    • Deficiency causes infertility, menstrual problems.
  10. Molybdenum
    • Sources: Onion, potato, bajra.
    • It is important for synthesis of haemoglobin and absorption of iron.
    • Deficiency causes irregular excretion of nitrogenous waste products.
  11. Selenium
    • Sources: Barley, garlic, orange juice.
    • It acts with vitamin E for slowing down ageing process.
    • Deficiency causes higher risk of cancer, cardiovascular disease.
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Disorders of digestive system

  1. Jaundice: The liver is affected , skin and eyes turn yellow due to deposit of bile pigment
  2. Vomiting: It is the ejection of stomach contents through the mouth. This reflex action is controlled by vomit centre in the medulla
  3. Diarrhoea: the abnormal frequency of bowel movement and increased liquidity of faecal discharge is known as diarrhea

  1. Constipation: in constipation, the faeces are retained within the rectum
  2. Indigestion: in this condition, the food is not properly digested leading to a feeling of fullness
  3. Gastroesophageal Reflux Disease (GERD) – A disease in which the ingested food leaks back from the stomach into the esophagus. It happens when the esophageal sphincter does not close well.
  4. Esophagitis – The inflammation of the esophagus commonly caused by infection. It is also a complication of GERD.
  5. Peptic Ulcer – A painful lesion of the stomach of small intestine.
  6. Gastritis – A disease that causes the inflammation of the lining of the stomach. It has many causes such as alcohol abuse, cigarette smoking, excessive consumption of coffee and aspirin.
  7. Colon Cancer – The uncontrolled growth of abnormal cells in the large intestine. It is third most common cause of cancer in Philippines.

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Digestion Vs Absorption

Digestion Absorption
1 Digestion is a mechanical and chemical break down of large food contents in to smaller particles that are easy to be absorbed Absorption is transferring the digested molecules across the gastrointestinal tract to the blood stream.
2 Digestion starts from the mouth.; Absorption starts from the stomach.
3 Digestion needs enzymes absorption does not need enzymes.
4 Most of the digestion takes place at duodenum absorption occurs mainly at ileum and jejunum
5 digestion functions upon large and complex digestive matter only. Absorption operates on both simple molecules of digestive and non-digestive matter
6 Digestion is always an active process and needs energy some of the absorption mechanisms do not need energy

Intracellular Digestion Vs Extracellular Digestion

Intracellular Digestion Extracellular Digestion
1 break down of materials into small components takes place inside the cell. break down of materials into smaller components takes place outside the cell.
2 Intracellular digestion occurs inside food vacuoles within the cell. Extracellular digestion occurs outside the cell in the lumen of the alimentary canal or on the decaying organic materials.
3 Ingestion occurs through a phagocytic vesicle in intracellular digestion. Ingestion occurs through the mouth in extracellular digestion.
4 The digestive enzymes in the lysosomes are secreted into the food vacuole in intracellular digestion The glands of the alimentary canal secrete digestive enzymes into the lumen in extracellular digestion. Fungi secrete digestive enzymes on the decaying organic materials.
5 Only the chemical digestion of food occurs during intracellular digestion. mechanical digestion and chemical digestion occur in extracellular digestion in animals
6 The nutrients diffuse into the cytoplasm through the membrane of the vacuole The nutrients are absorbed into the blood through the gut epithelia in extracellular digestion in animals. In fungi, nutrients are absorbed through the cell wall.
7 The indigestible materials are excreted through exocytosis in intracellular digestion. The indigestible materials are excreted through the anus in extracellular digestion

Glycogenesis Vs Glycogenolysis

Glycogenesis Glycogenolysis
1 Produce glycogen from glucose Breakdown of glycogen back to glucose
2 Can occur in all cells, but is an especially important function of liver and muscle cell Occurs in liver, kidney and intestine but not in muscle tissue because an essential enzyme is lacing

Gluconeogenesis Vs Glycogenolysis

Gluconeogenesis Glycogenolysis
1 It results in the formation of glucose molecules from non-carbohydrate sources. It results in the formation of glucose by breaking down glycogen molecules stored in the liver.
2 Amino acids, lactic acids are converted into glucose. Glycogen is broken down to form Glucose- 6-phosphate
3 It is anabolic process. It is hydrolytic process.
4 6 molecules of ATP are consumed per 1 glucose molecule synthesised. Less amount of ATP is consumed.

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Digestive Enzyme summary


Enzymes & Function


Enzymes & Function:


Enzymes & Function:

Small Intestine

Enzymes & Function:

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